For some, the right dosage can be found over-the-counter in concentrations as low as 2.5 percent or up to 10 percent, but for others, a prescription dosage is needed to see the best results. Prescription doses rarely go over 10 percent, as benzoyl peroxide is known to cause stinging, burning, itching, flaking, peeling, and redness2 when used in concentrations over 5 percent, but they may combine the benzoyl peroxide with other acne medications.
Considerations: Because tazarotene is a retinoid (vitamin A derivative), like Accutane, it should not be used by women who are pregnant because of potential harm to the fetus. Exposure to sunlight should be avoided. Wind or cold may be more irritating when taking tazarotene. Side effects occured in 10-30% of patients and included dry peeling skin, burning, stinging, dry skin, redness, and itchiness.
Our skin is a reflection of our overall health, which is why glowing, beautiful skin often results from proper care, hydration and eating a nutrient-dense diet. On the other hand, skin ridden with whiteheads, blackheads and other types of pimples can indicate oxidative damage, poor nutrition and hormonal imbalances — making it all the more important to find home remedies for acne.
How to Handle It: Consider salicylic acid your secret weapon. "This beta hydroxy acid helps remove excess oil and exfoliate dead cells from the skin's surface to keep pores clear," says Zeichner. Try Clinique's Acne Solution Clearing Gel, a two-time Best of Beauty winner that packs both salicylic acid and sea whip extract — an ingredient with skin-soothing properties — to help counteract the dryness sometimes caused by salicylic acid. The formula does double duty: It works as a spot treatment for mild to moderate acne and as a nightly allover treatment for pimple prevention. And since it dries clear, you can wear it to fight zits whenever, wherever.
Considerations: Regardless of the type of antibiotic prescribed, only about one half of patients respond. When antibiotics do produce results, these results are moderate at best.5-8 Oral antibiotics should be used for only a short period of time, up to 6 months. However, even within this short time frame, antibiotics have been implicated in the proliferation of resistant colonies of bacteria. Some antibiotics cause increased sensitivity to sunlight. Exposure to the sun could cause a rash, itchiness, or redness, and you may be burnt more easily, so you'll want to wear protective clothing and sunscreen.2 Side effects may include upset stomach, diarrhea, nausea, headache, vomiting, dizziness, or light-headedness as your body becomes accustomed to it.2 Minocycline is less prescribed because it works no better than any other antibiotic and comes with safety concerns, including the possibility of irreversible skin pigmentation.8-11
What's Going On: If it's big, red, and painful, you're probably experiencing cystic acne, one of the more severe types. "Cystic pimples are caused by genetics and hormonal stimulation of oil glands," says Zeichner. Not only are they large, but they're also notoriously tough to treat. They often recur in the same place, because even if you manage to get rid of one, it can keep filling up with oil again and again, like an immortal pimple.
Acne doesn’t discriminate based on age, race or gender. Between 40-50 million Americans have acne and know the daily struggle of living with this painful skin condition. 20% of them are adults. The other 80% are young people between the ages of 12 and 24, and one-quarter of these young people will suffer permanent scars on their skin from it. That means that 10 million young people will have permanent acne scarring.

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Accutane is especially good for cystic acne in women and body acne in men. “Oral vitamin A basically shuts down your sebaceous glands. If you suppress [them] for a long enough period, you can cure someone of their acne, and about 50 percent do hit that cure rate,” says Linkner. A course of Accutane can take about six to nine months. Sometimes patients need to repeat the course at a higher dosage in order to truly eliminate acne.
The first thing you need to do to take care of your skin is to use sunscreen. The best acne treatment never includes sunbathing and staying out in the sun unprotected will not reduce the number of blackheads or whiteheads you have. It will, however, lead to more skin problems down the road and can cause a breakout or two right now. Wrinkles, age spots and even skin cancer are on the agenda of someone who decides they don’t need to protect their skin.
The Body Shop Tea Tree Oil Products: Even though it’s not made in a lab, tea tree oil has been studied and proven to be a powerful anti-acne agent. The Body Shop takes advantage of this ingredient with their full line of tea tree oil products, from pure oil to face wipes to a clay mask, all containing tea tree oil. These products are best for oily skin, pimples, and cystic acne.
If you take a close look at the acne-fighting ingredients, you will find that no single ingredient does all the work to get rid of acne. Each one has a unique effect that plays a role in the elimination of acne, but only when they are used combined or in sequence in a system do they have ability to get rid of acne altogether. This is why it is so important to use an effective system for fight acne, not just a single product.
What it is: You may have heard of tretinoin in reference to "Retin-A" wrinkle treatments. Tretinoin is retinoic acid and vitamin A acid combined, and comes in various strengths in creams, gels, and liquids for topical use on the skin. It is used to treat acne and also to treat sun damaged skin or wrinkles and is usually applied once per day.1Learn more from the U.S. National Library of Medicine.
“My skin is very sensitive and I get rosacea and eczema (my skin pretty much hates the world). This is so gentle and non irritating, even during flare ups. My dermatologist said it's one of the most gentle face washes on the market. It's fragrance free and has a creamy almost gel like consistency, not as watery as some other non foaming cleansers. I don't wear makeup, but I don't think this would remove makeup if you did, so you'd probably need to remove makeup before using this cleanser.”
You will see the results from the top performers in the comparison chart. Although any of these treatment systems can safely and effectively help reduce blemishes, Exposed Skin Care stands above the rest as the best acne treatment system. All the products are safe and regulated by the FDA, but Exposed Skin Care also works for a variety of skin types, including sensitive skin. The thing we like most about Exposed Skin Care is the 6-month money back guarantee. Many blemish products expect you to use them for six to eight weeks before you see results and then only provide you with a 1-month guarantee. If you purchase individual products in the store, you are stuck with them, since many do not come with any guarantees. Exposed Skin Care allows you to give their product a fair trial before you decide if it is working for your skin.
According to medical research, tea tree oil gels containing 5 percent tea tree oil may be as effective as medications containing 5 percent benzoyl peroxide. (10) Researchers do indicate that tea tree oil may work more slowly for some individuals, so try to be patient. To make a simple home remedy for acne using tea tree oil mix 4–8 drops of tea tree oil and one teaspoon of coconut oil or jojoba oil. Dap lightly onto the problem areas. Slight tingling is normal, but if the application causes lots of burning then discontinue use. Always use a carrier oil, as tea tree oil can be too harsh when applied directly to skin.

Genetics play a big part in who gets acne and how severely, but each blemish can be blamed on some combination of sebum production, a bacteria called Propionibacterium acnes (P. acnes), plugged follicles, and inflammation. Finding a good treatment is really about finding the right combination of ingredients to troubleshoot each of those issues. Some factors that might worsen acne include hormones, certain medications, diet and stress.
If you’re looking for a hormonal solution to your acne but don’t want to take a combined oral contraceptive, spironolactone may be the answer. This oral medication is a potassium-sparing diuretic originally designed to treat high blood pressure, but is now also used to treat acne. It mainly functions by reducing sebum production, leading to less acne formation13. If you are able to get pregnant, you don’t necessarily need to take a combined oral contraceptive, but you will want to use some form of birth control since spironolactone, like Accutane, is a well-known teratogen and is known for causing birth defects.
Whether it’s just or not, you are judged by your appearance: the clothes you wear, your hairstyle, your body language. And if you have acne, life can be more difficult for you. You may feel uncomfortable in social settings. You may lose your confidence. It could destroy intimacy with someone you care about. If your poor self-esteem affects your job performance, then having acne could even have a negative impact on your income and career advancement. There’s no such thing as ‘growing out of acne’. It’s an issue that needs to be taken seriously. The only way to fight acne is by treating it. And to fight acne head-on, you need to find the best acne treatment for you.
Just as there are no bells and whistles with Purpose above, there are none with this baby-mild product that renowned dermatologists swear by. So why is this $10 cleanser such a must-have? It's creamy, simple and isn't loaded with chemicals or perfumes that can irritate the skin. Cetaphil products are revered in the industry and their cleanser is one of the best drugstore buys out there. Period.
What it is: Originally under the brand name "Accutane" but now available only in generic form, isotretinoin is a derivative of vitamin A taken in pill form for 15-20 weeks. Doctors normally prescribe it for people with "severe nodular acne" that does not respond to other treatments. Nodules are inflammatory lesions with a diameter of 5mm or more. A single course of 15-20 weeks has been shown to result in complete clearing and long-term remission of acne in many people.1-2 Learn more on the Accutane page of acne.org.
Clean your face really well using a mild face cleanser and gently pat dry. Let your skin further air dry and don’t put anything else on it. Don’t put anything else on your face like moisturizer, serum, toner, etc. After a half hour, carefully check your cheeks, chin, forehead and nose, with a hand mirror, for any shine. Also, check if your skin feels tight when you smile or make exaggerated facial expressions.
Sometimes birth control alone isn’t enough to really make a difference in hormonal acne. That’s when your doctor might recommend adding in an androgen blocker such as Spironalactone. Spiro (as it’s called) minimizes the amount of androgen hormones in circulation by blocking the receptors that bind with testosterone. When these pills are taken at the same time as an oral contraceptive, 90 percent of women see an improvement in breakouts, according to Linkner. The drug is sometimes prescribed to women with PCOS (polycystic ovarian syndrome) to relieve androgen-related symptoms like excessive hair growth, hypertension, oily skin, and acne.
This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
The Effaclar Medicated Cleanser from La Roche-Posay is made especially for users with oily skin. The 2% salicylic acid concentration slows down sebum production without completely stripping the skin of its natural oil. Therefore, it won’t dry out your face, but it does reduce shine. And the key ingredient, zinc pidolate, soaks up excess oil and removes impurities.
Shah often recommends over-the-counter retinols or prescription retinoids to her acne-prone patients. “I find that compared to other treatments they are beneficial for not just treating acne but also preventing new acne from forming as they help prevent that initial stage of the follicle getting clogged,” she says. “They can also help with some of the post acne [problems] such as hyperpigmentation.” But keep in mind if you have sensitive skin (or eczema or rosacea), a prescription retinoid might be too strong an option. However, your dermatologist can recommend an over-the-counter retinol with a low concentration (0.1 to 0.25 percent), which might be better tolerated. Retinol also isn’t a quick fix. It takes time to see results, and it’s something you’ll have to keep using to maintain its benefits. Shah also mentions that retinol plays well with other acne treatments on the list. "Retinol can be combined with other over-the-counter or prescription medications such as benzoyl peroxide, topical antibiotics, and oral medications. The right combination depends on the severity of the acne and your skin type."

Benzoyl peroxide attacks the P. acnes bacteria. However, one of its main side effects is dryness: If you’re going to use anything with benzoyl peroxide, make sure to moisturize afterwards. Sulfur and azelaic acid are less common and less severe alternatives to benzoyl peroxide. Dr. Peter Lio, assistant professor of clinical dermatology at Northwestern University, says sulfur-based treatments are “a good fit for patients who can’t tolerate the side effects of benzoyl peroxide.”
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